UI researchers create a bio patch to regrow bone - KWWL - Eastern Iowa Breaking News, Weather, Closings

UI researchers create a bio patch to regrow bone

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University of Iowa researchers have developed an implantable bio patch that regrows bone in the living body, creating a new way of treating wounds.

Dr. Aliasger Salem, professor of pharmaceutical sciences says the three-year research is still in the early stages, but the goal of the growing bone is to improve treatment in rebuilding bone in the gums area and other bone fractured areas.

“If you have a bone fracture where the defect site is too large for a bone to grow across the defect site by itself then this can facilitate that repair,” said Salem.

Researchers composed of professors and students say this growing bone works much like a bandage, putting DNA into a tiny particle that delivers bone-producing instructions using existing cells in the living body.

Sheetal D’Mello, a graduate research assistant is the main one assigned to this project as part of her thesis.

“It was my role in fabricating the scaffolds that contain this growth factor that promote bone regeneration,” said D’Mello.

She says it took about four weeks to get a complete regeneration of the bone in animal models they used.

Researchers say it’s all part of the University of Iowa’s innovative and cutting-edge research and technology.

“Creating the type of leaders that will go on to create the next generation of therapies for patients and that’s something that’s a real strength of our institution,” said Salem

With the preliminary studies, they’re hoping to use their cutting-edge research to help save lives.

“In the future it has a lot of clinical applications in patients with bone defects, so I hope it goes to clinics and it would make me feel good about all of these experiments,” said D’Mello.

Professor Salem says there’s still a great deal of work to be done before they can move forward and use it for humans.

He says they’re safety testing and looking at the ability to translate this to humans, but there are still a few years of work involved.

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